Wyatt Technology WH-03 Multi-Angle Light Scattering Detector

The Wyatt Technology WH-03 Heleos II DAWN 8 is a multi-angle light scattering (MALS) detector designed for absolute molecular weight, size, and conformation analysis of proteins, polymers, nanoparticles, and other macromolecules in solution. It integrates with HPLC, SEC-MALS, GPC-MALS, and FFF systems to provide absolute molar mass measurements without reliance on chromatographic calibration standards. Key specifications include 8-angle (HELEOS II) detection, molecular weight range about 200 Da to 1 GDa, and molecular size range about 10 nm to 500 nm in radius of gyration, with a high-stability laser at 658 nm and ASTRA software compatibility. Common applications are biopharmaceutical research, polymer analysis, protein characterization, and nanotechnology workflows in pharmaceutical, biotechnology, polymer, and nanotech laboratories.